• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The present invention relates to a method for drying channels of an endoscope, comprising the following steps: a) connection of the endoscope, in particular via specific connectors, to a plasma drying unit, b) injection of a gas neutral in the endoscope channels for a period of between 10 and 60 seconds, the gas flow being low, the gas being injected at a temperature between 10 ° C and 30 ° C, to remove the residual water, then c ) drying the channels of the endoscope for a period of between 30 and 90 seconds, by injecting a gas at a high rate, the gas being injected at a temperature between 30 ° C and 60 ° C.
    公开号:FR3026303A1
    申请号:FR1459071
    申请日:2014-09-25
    公开日:2016-04-01
    发明作者:Liviu Daniel Vinteler
    申请人:Plasmabiotics SAS；
    IPC主号:
    专利说明:

    [0001] The present invention relates to a rapid method of drying an endoscope with one or more channels. Endoscopy is a medical imaging technique widely used today, particularly because of its ease of realization, accuracy and low invasiveness endoscopes are thus used either to establish a diagnosis (diagnostic endoscopy) or to treat a disease or trauma (operative endoscopy). Their handling and cleaning are however very specific: cleaning and disinfection are necessary.
    [0002] Conventionally, the endoscope is cleaned immediately after the examination, with a suitable non-abrasive detergent, then rinsed. The total time of this cleaning step should not be less than 15 minutes. Then, the endoscope is disinfected: it is immersed in a disinfectant solution, then rinsed again. Finally, it is partially dried using a medical air gun. This last step lasts approximately 5 minutes. The result obtained is unsatisfactory. For more efficient drying of an endoscope, there are temperature-sensitive endoscope drying enclosures (ESET). According to the manufacturers, the drying is carried out between 15 and 90 minutes.
    [0003] Such a method is long, and must be renewed after each use. There is therefore a need for a process for drying endoscopes that is efficient, fast, and does not damage the endoscopes. In addition, there is a need for a drying process which ensures the microbiological safety of this type of medical equipment. The present invention makes it possible to respond to these problems. In particular, the present invention enables the endoscopes to be dried effectively and quickly. It is also used in conditions compatible with the sensitivity of the devices.
    [0004] The present invention thus relates to a method of drying channels of an endoscope, comprising the following steps: a) connection of the endoscope, in particular via a specific connection, to a plasma drying unit, b) injection of a neutral gas in the endoscope channels for a period of between 10 and 60 seconds, the flow rate of the gas being low, the gas being injected at a temperature between 10 ° C and 30 ° C, in particular to remove the residual water, c) drying the channels of the endoscope for a period of between 30 and 90 seconds, by injecting a gas at a high rate, the gas being injected at a temperature between 30 ° C and 60 ° C. The gas used in step c) may be neutral or a plasma generated by an electric discharge in a stream of dinitrogen or air. Preferably, the overall duration of steps a) to c) is between 1 and 5 minutes. This allows for drying and, when the gas is a plasma, ultrafast disinfection.
    [0005] By "cleaning" is meant that the endoscope has undergone a washing operation. This operation can be done manually or by washing machine. The endoscope is clean of dirt and ready for a disinfection cycle. Preferably in the method according to the invention, the endoscope is cleaned beforehand.
    [0006] "Disinfection" or "disinfecting" an element means the operation of voluntary and temporary elimination of certain germs, so as to stop or prevent an infection or the risk of infection or superinfection by microorganisms (bacteria, protozoa or viruses) pathogenic and / or undesirable. Disinfection is distinct from sterilization, which consists of the definitive elimination of certain germs.
    [0007] Disinfection involves killing or inactivating pathogenic microorganisms of contaminated elements, altering their structure or inhibiting their metabolism or some of their vital functions. Disinfection is therefore a special mode of decontamination, i.e. targeted on pathogenic microorganisms (bacteria, protozoa and viruses). Preferably in the method according to the invention, the endoscope is chemically disinfected prior to steps a) to c).
    [0008] By chemical disinfection is meant disinfection by means of chemicals such as enzymatic detergents (amylases, lipases, proteases ...), amino compounds, glucoprotamine, peracetic acid and hydrogen peroxide.
    [0009] The endoscope according to the invention is any type of endoscope. It consists of a tube with channels (which will be introduced into the body of the patient), to which are connected a control handle and a light guide that allows the attachment of a camera and light. The endoscope may be chosen among bronchoscopes, colonoscopes, gastroscopes, rectoscopes, laparoscopes and arthroscopes. The first step of the method according to the invention, i.e. step a), comprises connecting the endoscope to a drying unit in order to inject the gas. This connection can be done either by the piston cage of the endoscope, or by its proximal end. In addition, this connection can be done by specific connectivity, for example by that marketed by Lancer Getinge. An example of this connection by the piston cage is shown in Figure 1, and an example of this connection by the proximal end is shown in Figure 2.
    [0010] Then, during step b), a neutral gas is injected into the endoscope channels for a period of between 10 and 60 seconds, the flow rate of the gas being low, the gas being injected at a temperature of between 10 ° C. and 30 ° C, especially to remove residual water. Preferably, the neutral gas is dinitrogen, or air.
    [0011] This step b) is short, i.e. a few tens of seconds; it allows the effective evacuation of the liquid contained in the channels of the endoscope. This step b) makes it possible in particular to eliminate the residual water, in particular the water resulting from the previous step of chemical disinfection of the endoscope.
    [0012] Finally, the process according to the invention comprises a c) drying step for a period of between 40 and 60 seconds, by injecting the gas at a temperature between 30 ° C and 60 ° C. Preferably, the gas used in this step c) is a neutral gas, preferably dinitrogen or air. Alternatively, the gas is a plasma generated by an electric discharge in a stream of dinitrogen or air. The drying is done by gas injection, and the disinfection is simultaneously drying when the gas is a plasma.
    [0013] Preferably, the drying c) is by injection of the gas into the channels of the endoscope either by the piston cage or by its proximal end. Preferably, the plasma is obtained by activation by an electric field, at atmospheric pressure, of the stream of dinitrogen. Preferably, the plasma is used at a temperature between 20 and 80 ° C, preferably at a temperature between 30 and 50 ° C. Plasmas can be considered as the fourth state of matter, in order of ascending order of energy the solid, liquid and gaseous states. This fourth state is strictly speaking a medium of low density, globally neutral, composed of atoms, molecules, ions and free electrons. Plasmas manufactured by humans are most often derived from a gas or a mixture of gases (Ar, He, air, O2, N2,...) Subjected to an electric field (between two electrodes).
    [0014] The zone where the gas is subjected to the electric field is called the "electric discharge" zone, the plasma flux emanating from this discharge being in the "post-discharge" zone. Conventionally, the plasma is generated by an electric discharge (by means of an electric field established between two electrodes) in an initially inert gas stream or gas mixture. There are two areas of plasma: the discharge zone and the post-discharge zone. In the discharge zone, we can find electrons, ions, atoms and molecules in different energetic states. In the post-discharge zone, the active species found are rather neutral atoms and molecules, which are in excited or metastable states.
    [0015] Preferably, the plasma used according to the invention is a cold plasma obtained in the post-discharge zone. Preferably, it is precisely obtained by subjecting the stream of dinitrogen to a pulsed electric field established between two or four point-shaped electrodes. The electric field is created by a high voltage pulse generator (kV). Preferably, the stream of dinitrogen is created upstream of its introduction into the generator by generating a stream of dinitrogen with a flow rate of about 1 to 100 L / min, preferably at a pressure of 1 to 2 bars. Flow control of the gas flow is carried out using commercially available devices, such as the Bronkhorst Mass-view flow controller. Preferably, the plasma used according to the invention is generated as follows: The dinitrogen introduced into the generator passes through a discharge chamber (reactor) consisting of a thermal insulating material resistant and stable at very high temperatures (ie greater than 900 ° C, preferably around 1000 ° C). Preferably, the thermal insulating material resistant and stable at very high temperatures is a mixture of ceramic / glass, for example the Macor material marketed by Corning Inc. A channel with a variable diameter, ie of the order of a few mm, pierced inside a cube of resistant thermal insulation material and stable at very high temperatures, preferably in Macor, is used for the passage of gas. One or two channels with a diameter of 1 mm are drilled perpendicular to the channel of the gas flow. The pure tungsten electrodes are inserted in these channels and sealed. The distance between the tips of the electrodes is a few mm. Once the dinitrogen flow is established in the reactor, the nanosecond high voltage pulse generator can be started. The high voltage (1-10 kV) created by the generator is used to establish an electric field between the electrodes in the reactor, with a frequency between 10 and 100 kHz, preferably between 30 and 80 kHz. The voltage between the electrodes increases and once the ignition voltage between the electrodes is reached, the discharge occurs in the reactor. During the priming, the voltage between the electrodes drops very rapidly and the discharge current is in the form of a peak with a width at mid-height of the order of 10 ns. The plasma created during this discharge has a temperature around 300-340 K (i.e. 26.85-66.85 ° C) and it spreads over a few meters in endoscope tubes. Preferably, the apparatus used to generate the plasma is the InPulse ONE generator, marketed by PlasmaBiotics SAS.
    [0016] Preferably, the plasma according to the invention is obtained and used at atmospheric pressure. More preferably, the plasma is obtained in the drying plasma unit by the following steps: passing a stream of dinitrogen, having a flow rate of about 1 to 100 l / min, in the unit; then - submission of the resulting stream to an electric shock.
    [0017] The method according to the invention comprises bringing the channels of the endoscope into contact with the plasma. Preferably, the contacting is done when the plasma has a temperature between 20 and 80 ° C, preferably a temperature between 30 and 50 ° C. Preferably, the element is brought into contact with the plasma for a very short duration, i.e., of about 45 to 60 seconds. The invention will now be exemplified with the aid of the examples which follow, which are not limiting.
    [0018] Example: The following tests are carried out, to compare the drying method according to the invention with conventional methods with drying enclosures thermosensitive endoscopes (E SET).
    [0019] Two endoscopes are used to perform these tests: - a Fujinon EC530; and - an Olympus CF2OHL. The drying times are indicated in the following table: Endoscope type Drying time by Drying time in ESET (comparative) Method according to the invention FUJINON EC530 2 min and 15 sec 15 to 90 min Olympus CF2OHL 2 min 15 to 90 min The method according to the invention therefore allows drying 8 to 45 times faster. The biocidal effect of the nitrogen plasma, incorporated in the method according to the invention, is demonstrated on tubes of 3 m in length: Germs Tube of 4 mm diameter Tube of 2.5 mm diameter Tube of 1 , 5 mm diameter P. aeruginosa, 5 log 4.6 log 4.2 log drying plasma N2 P. aeruginosa, 3.5 3.5 3.5 drying N2 10
    权利要求:
    Claims (10)
    [0001]
    REVENDICATIONS1. Method for drying channels of an endoscope, comprising the following steps: a) connection of the endoscope, in particular via specific connectors, to a drying plasma unit, b) injection of a neutral gas into the endoscope channels for a time of between 10 and 60 seconds, the flow rate of the gas being low, the gas being injected at a temperature of between 10 ° C. and 30 ° C., in particular for eliminating the residual water, and then c) drying the cooling channels. the endoscope for a period of between 30 and 90 seconds, by injecting a gas at a high rate, the gas being injected at a temperature between 30 ° C and 60 ° C. 15
    [0002]
    2. Method according to claim 1, characterized in that the gas used in step c) is neutral, or is a plasma generated by an electric discharge in a stream of dinitrogen.
    [0003]
    3. Method according to claim 1 or 2, characterized in that the neutral gas is dinitrogen or air. 20
    [0004]
    4. Method according to claim 1 or 2, characterized in that the plasma is obtained by activation by an electric field, at atmospheric pressure, the stream of dinitrogen.
    [0005]
    5. Method according to one of claims 2 or 4, characterized in that the plasma is a cold plasma obtained in the post-discharge zone.
    [0006]
    6. Method according to one of claims 1 to 5, characterized in that the drying c) is by injection of the gas in the channels of the endoscope by the piston cage, or by its proximal end. 30
    [0007]
    7. Method according to one of claims 2 or 4 to 6, characterized in that the plasma is obtained in the plasma drying unit, by the following steps: - passage of a stream of nitrogen or air , having a flow rate of about 1 to 100L / min, in the unit; then - submission of the resulting stream to an electric shock.
    [0008]
    8. Method according to one of claims 2 or 4 to 7, characterized in that the plasma is used at a temperature between 20 and 80 ° C, preferably at a temperature between 30 and 50 ° C.
    [0009]
    9. Method according to one of claims 1 to 8, characterized in that the overall duration of steps a) to c) is between 1 and 5 minutes.
    [0010]
    10. Method according to one of claims 1 to 9, characterized in that the endoscope is chemically disinfected prior to steps a) to c) .15
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    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    FR2705896A1|1993-06-03|1994-12-09|Mariotti Bernard|Device for decontaminating, disinfecting and drying sealed endoscopes|
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    CN103585650B|2013-07-09|2016-04-06|西安交通大学|A kind of low temperature plasma endoscope sterilizing device and method|FR3052073A1|2016-06-02|2017-12-08|Plasmabiotics|DRYING METHOD OF MEDICAL DEVICE|
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    EP3731879A4|2017-12-30|2021-09-08|3M Innovative Properties Company|Plasma sterilization and drying system and methods|
    CN110464858A|2019-07-15|2019-11-19|老肯医疗科技股份有限公司|A kind of cabin for hydrogen peroxide low-temperature plasma sterilizer|
    KR102228166B1|2019-09-03|2021-03-16|삼육대학교산학협력단|Guide device for blind people using electronic stick and smartphone|
    法律状态:
    2015-09-29| PLFP| Fee payment|Year of fee payment: 2 |
    2016-04-01| PLSC| Publication of the preliminary search report|Effective date: 20160401 |
    2016-09-26| PLFP| Fee payment|Year of fee payment: 3 |
    2017-09-28| PLFP| Fee payment|Year of fee payment: 4 |
    2018-09-24| PLFP| Fee payment|Year of fee payment: 5 |
    2019-09-25| PLFP| Fee payment|Year of fee payment: 6 |
    2020-09-14| PLFP| Fee payment|Year of fee payment: 7 |
    2021-09-21| PLFP| Fee payment|Year of fee payment: 8 |
    优先权:
    申请号 | 申请日 | 专利标题
    FR1459071|2014-09-25|
    FR1459071A|FR3026303B1|2014-09-25|2014-09-25|DRYING METHOD OF MEDICAL DEVICE|FR1459071A| FR3026303B1|2014-09-25|2014-09-25|DRYING METHOD OF MEDICAL DEVICE|
    JP2017516779A| JP6730265B2|2014-09-25|2015-09-25|How to dry a medical device|
    US15/514,008| US10251963B2|2014-09-25|2015-09-25|Method for drying a medical device|
    EP15778379.6A| EP3197506B1|2014-09-25|2015-09-25|Method for drying the channels of an endoscope|
    CA2962141A| CA2962141A1|2014-09-25|2015-09-25|Method for drying a medical device|
    DK15778379.6T| DK3197506T3|2014-09-25|2015-09-25|PROCEDURE FOR DRYING AN ENDOSCOPE CHANNELS|
    AU2015323547A| AU2015323547B2|2014-09-25|2015-09-25|Method for drying a medical device|
    PCT/FR2015/052557| WO2016046503A1|2014-09-25|2015-09-25|Method for drying a medical device|
    CN201580052229.2A| CN106796083B|2014-09-25|2015-09-25|Method for drying medical instruments|
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